A High Throughput Assay for Collagen Secretion Suggests an Unanticipated role for Hsp90 in Collagen Production

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From: Biochemistry(Vol. 57, Issue 19)
Publisher: American Chemical Society
Document Type: Report
Length: 54 words

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Abstract :

This study developed a cell-based, high-throughput luminescent assay of collagen type I secretion and used it to screen for small molecules that selectively enhance or inhibit that process and highlights the value of a cell-based high-throughput screen for selective modulators of collagen secretion and suggest an unanticipated role for cytosolic Hsp90 in collagen secretion.

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Gale Document Number: GALE|A542093872