Key Points for Practice
* The KIDs List includes a limited number of medications to avoid or use with caution in children older than one year. More medications are included for infants and neonates.
* Medications such as fluoroquinolones and antidepressants are not included because there are no effective alternatives for some indications.
* Aspirin and other salicylates should be used with caution in suspected viral respiratory illness but may be necessary for other indications.
From the AFP Editors
Adverse drug reactions are responsible for approximately 4% of admissions to children's hospitals. Up to 18% of hospitalized children experience at least one adverse drug reaction. Approximately one-half of pediatric adverse drug reactions affect children between one and 10 years of age, with the other half evenly split between infants and children older than 10 years. Because one-half of medications are not currently labeled for children, off-label prescriptions are common. The Pediatric Pharmacy Association produced a list of key potentially inappropriate drugs in pediatrics, or the KIDs List, to guide physicians who treat children.
Potentially Inappropriate Medications
The panel defined potentially inappropriate medications as medications or medication classes that generally should be avoided in children younger than 18 years because they pose an unnecessarily high risk and for which a safer alternative...