Total synthesis of mucocin

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From: Journal of the American Chemical Society(Vol. 120, Issue 44)
Publisher: American Chemical Society
Document Type: Article
Length: 55 words

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Abstract :

Research was conducted to examine the synthesis of the potent antineoplastic agent, mucocin, which was achieved in 20 steps from cyclododecatriene. The "naked" carbon skeleton method was utilized as well as the double AE reaction and the double AD reaction. Simultaneous two ring closure reactions provided the tetrahydrofuran and tetrahydropyran rings in one single step.

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Gale Document Number: GALE|A53409974