Reinforcing antibacterial hydrogels through electrospun nanofiber layers for soft tissue engineering.

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Date: Dec. 2020
From: Journal of Polymer Research(Vol. 27, Issue 12)
Publisher: Springer
Document Type: Report; Brief article
Length: 241 words

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Abstract :

Keywords: Antibacterial hydrogels; Electrospun nanofibers; Reinforcement; Mechanical strength; Soft tissue engineering Abstract Hydrogels are polymeric substances with hydrophilic features, which make them capable of holding large volume of liquids in their three-dimensional network structures. Hydrogels are finding wide ranges of applications in several biomedical, industrial, and environmental fields. In this study, hydrogels were prepared using chitosan powders, and reinforced with electrospun poly (methyl methacrylate) (PMMA) and poly vinyl chloride (PVC) nanofibers. The chitosan hydrogels were produced by dissolving chitosan in 1% acetic acid solution and mixing thoroughly. Gentamycin, an antibacterial agent, was also added to further increase the effectiveness of hydrogels for biomedical purposes. The prepared hydrogels were subjected to swelling, Fourier-transform infrared spectroscopy (FTIR) and compression tests. The test results showed that hydrogel provided very high-water absorption capacity (10--11 folds). FTIR studies conducted on the hydrogel samples with different percentages of inclusions revealed that some of the compounds were covalently bonded in the structures, which directly affect the mechanical strength and liquid absorption capacity. The compression tests performed at different loads indicated that PVC and PMMA nanofibers reinforced hydrogels provided up to 75% much higher compression strengths when compared to the base-case (without any reinforcement). Author Affiliation: (1) Department of Mechanical and Mechatronics Engineering, Fujairah Men's College, Fujairah, UAE (2) Department of Mechanical Engineering, Wichita State University, 1845 Fairmount, 67260--0133, Wichita, KS, USA (c) Article History: Registration Date: 11/17/2020 Received Date: 08/03/2020 Accepted Date: 11/17/2020 Online Date: 11/20/2020 Byline:

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Gale Document Number: GALE|A647143303