Is Vitamin D Deficiency the Cause or the Effect of Systemic Lupus Erythematosus: Evidence from Bidirectional Mendelian Randomization Analysis.

Citation metadata

Date: Sept. 21, 2022
Publisher: Hindawi Limited
Document Type: Article
Length: 4,840 words
Lexile Measure: 1260L

Document controls

Main content

Abstract :

Background. Vitamin D deficiency is common in patients with systemic lupus erythematosus (SLE). Observational studies have reported that it is associated with SLE. In this bidirectional Mendelian randomization (MR) study, we explored the genetic association between serum vitamin D (VD) levels and SLE using two models. Methods. Genetic variants associated with vitamin D (n=304,181), 25-hydroxyvitamin D levels (n=401,460), and SLE (n=213,683) at genome-wide significance (P

Source Citation

Source Citation   

Gale Document Number: GALE|A720580821