Preparation and in vitro studies of fixed-dose tablet combination of repaglinide and metformin.

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From: Istanbul Journal of Pharmacy(Vol. 51, Issue 1)
Publisher: Istanbul University Press
Document Type: Article
Length: 3,810 words
Lexile Measure: 1390L

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Abstract :

Background and Aims: The study aimed to design a Fixed-dose tablet formulation of Metformine and Repaglinide. Methods: Wet granulation method was used to prepare tablet formulations. Characterization studies and dissolution studies were performed. Results: A stable formulation was developed according to the requirements of the pharmacopoeia criteria. This new formulsation dissolution results showed that Repaglinide and Metformin HCl dissolved more than 85% from film tablets at 15 minutes. Conclusion: Thus, an alternative product to the market product was developed. Keywords: Fixed-Dose Tablet, Metformin, Repaglinide

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Gale Document Number: GALE|A664447578