In-vitro antibacterial activity of some essential oils against clinical isolates of Acinetobacter baumannii

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Date: January-March 2014
From: Indian Journal of Medical Microbiology(Vol. 32, Issue 1)
Publisher: Elsevier B.V.
Document Type: Article
Length: 1,016 words
Lexile Measure: 1590L

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Byline: Gopinath. Prakasam, Manju. Bhashini, Lakshmipriya, S. Ramesh

Dear Editor,

Until 1970s, Acinetobacter baumannii was considered to be a rare cause of nosocomial infections. However, the incidence of Acinetobacter infections has reached a point of concern and poses a threat to debilitated patients around the world. [sup][1] The clinical importance of Acinetobacter has improved rapidly in the last 20 years, due to the world-wide expression of intensive care units that led to a change in the type of infections and the emergence of multi drug resistant Acinetobacter isolates. [sup][2] Essential oils have been implicated in a wide array of applications for several 1000 years owing to their antimicrobial properties as alternative medicine. [sup][3] Thus, the development of resistance to antibiotics is believed to be counteracted by the use of natural herbal medicine are being considered to be the need of the hour. The present study was undertaken to determine the in-vitro antibacterial activity of clove, peppermint and eucalyptus oils against clinical isolates of A. baumannii. Essential oils were procured from Tegraj and Co (P) Ltd, India and their purity was about 99.9%. The major constituents were found to be eugenol (84.2%), eugenyl acetate (9.7%) for clove oil. P-menthone (19.5%), menthol (63.5%) and 1,8-cineole (74.3%), a-terpinenol (10.3%) for peppermint oil and eucalyptus oil respectively. We tested a total of 50 isolates of A. baumannii from different clinical specimens that includes blood (15), endotracheal aspirates (14), bronchoalveolar lavage (6), pus (6), urine (5) and sputum (4). Minimum inhibitory concentrations (MICs) were determined for these oils by...

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Gale Document Number: GALE|A355830932