Role of intracellular Ca2+ in stimulation-induced increases in transmitter release at the frog neuromuscular junction

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From: Journal of General Physiology(Vol. 104, Issue 2)
Publisher: Rockefeller University Press
Document Type: Article
Length: 69 words

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Abstract :

Resting intracellular Ca2+ levels regulate the stimulation-induced variations in end-plate potential (EPP) amplitude at the neuromuscular junction in frogs when extracellular Ca2+ levels are increased. A rise in the magnitude of augmentation component of enhanced transmitter release from the junction causes the increase in EPP amplitude. The Ca2+ levels are functional at many sites in the nerve terminal, with the facilitation and potentiation components of release representing various processes.

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Gale Document Number: GALE|A16151305