Changes in Healthcare Spending After Diagnosis of Comorbidities Among Endometriosis Patients: A Difference-in-Differences Analysis

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From: Advances in Therapy(Vol. 34, Issue 11)
Publisher: Springer
Document Type: Report
Length: 409 words

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To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: Byline: Andrew J. Epstein (1), Ahmed M. Soliman (2), Matthew Davis (1), Scott J. Johnson (1), Michael C. Snabes (2), Eric S. Surrey (3) Keywords: Comorbidity; Endometriosis; Gynecology; Healthcare expenditures Abstract: Introduction We sought to characterize changes in healthcare spending associated with the onset of 22 endometriosis-related comorbidities. Methods Women aged 18--49 years with endometriosis (N = 180,278) were extracted from 2006--2015 de-identified Clinformatics.sup.[R] DataMart claims data. For 22 comorbidities, comorbidity patients were identified on the basis of having a first comorbidity diagnosis after their initial endometriosis diagnosis. Controls were identified on the basis of having no comorbidity diagnosis and were matched 1:1 to comorbidity patients on demographics and baseline spending. Total medical and pharmacy spending was measured during 12 months before and after each patient's index date (first comorbidity diagnosis for comorbidity patients, and equal number of days after earliest endometriosis claim for controls). Pre--post spending differences were compared using difference-in-differences linear regression. Total and comorbidity-related cumulative spending per patient for all endometriosis patients were calculated annually for the 5 years following endometriosis diagnosis. Results The number of endometriosis patients with each comorbidity varied between 121 for endometrial cancer and 16,177 for fatigue. Healthcare spending increased significantly with the onset of eight comorbidities: breast cancer, ovarian cancer, pregnancy complications, systemic lupus erythematosus/rheumatoid arthritis/Sjogren's/multiple sclerosis, infertility, uterine fibroids, ovarian cyst, and headache [p Conclusion For all but one of the 22 comorbidities associated with endometriosis, comorbidity onset was associated with a relative increase in total healthcare spending. Funding AbbVie Inc. Author Affiliation: (1) Medicus Economics, Milton, MA, USA (2) AbbVie, North Chicago, IL, USA (3) Colorado Center for Reproductive Medicine, Lone Tree, CO, USA Article History: Registration Date: 10/10/2017 Received Date: 07/08/2017 Online Date: 03/11/2017 Article note: Enhanced content To view enhanced content for this article go to Electronic supplementary material The online version of this article (doi: 10.1007/s12325-017-0630-8) contains supplementary material, which is available to authorized users.

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Gale Document Number: GALE|A515666393