Synthesis and biophysical characterization of oligonucleotides containing a 4'-selenonucleotide

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From: Journal of the American Chemical Society(Vol. 130, Issue 27)
Publisher: American Chemical Society
Document Type: Article
Length: 27 words

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Abstract :

The synthesis and biophysical properties of oligonucleotides containing 5-methyl-4'-selenouridine (4'-Se-rT) are described. 4'-Se-rT modification of A-RNA and hybrid duplexes has led to the increase in binding affinity.

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Gale Document Number: GALE|A181690391