Maternal obesity and gestational diabetes are associated with placental leptin DNA methylation

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Publisher: Elsevier B.V.
Document Type: Article
Length: 222 words

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To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajog.2014.06.037 Byline: Corina Lesseur, David A. Armstrong, Alison G. Paquette, Zhigang Li, James F. Padbury, Carmen J. Marsit Abstract: In this study, we aimed to investigate relationships between maternal prepregnancy obesity and gestational diabetes mellitus and placental leptin DNA methylation. Author Affiliation: (a) Department of Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth, Hanover, NH (b) Section of Biostatistics and Epidemiology, Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH (c) Department of Pediatrics, Women and Infants Hospital of Rhode Island, Brown University, Providence, RI Article History: Received 12 March 2014; Revised 20 May 2014; Accepted 17 June 2014 Article Note: (footnote) The views expressed herein are those of the authors and do not necessarily represent the official views of the supporting institutions., This study was supported by the National Institutes of Health (NIH) through the following grants: R01MH094609 (NIH-National Institute of Mental Health), R01ES022223 (NIH-National Institute of Environmental Health Sciences), P01 ES022832 (NIH-National Institute of Environmental Health Sciences), RD83544201 (US Environmental Protection Agency), and P30CA23108 (NIH-National Cancer Institute)., The authors report no conflict of interest., Cite this article as: Lesseur C, Armstrong DA, Paquette AG, et al. Maternal obesity and gestational diabetes are associated with placental leptin DNA methylation. Am J Obstet Gynecol 2014;211:654.e1-9.

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Gale Document Number: GALE|A393153263