Risk of total and aggressive prostate cancer and pesticide use in the agricultural health study

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From: American Journal of Epidemiology(Vol. 177, Issue 1)
Publisher: Johns Hopkins University Press
Document Type: Author abstract
Length: 211 words

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Abstract :

Because pesticides may operate through different mechanisms, the authors studied the risk of prostate cancer associated with specific pesticides in the Agricultural Health Study (1993-2007). With 1,962 incident cases, including 919 aggressive prostate cancers among 54,412 applicators, this is the largest study to date. Rate ratios and 95% confidence intervals were calculated by using Poisson regression to evaluate lifetime use of 48 pesticides and prostate cancer incidence. Three organophosphate insecticides were significantly associated with aggressive prostate cancer: fonofos (rate ratio (RR) for the highest quartile of exposure (Q4) vs. nonexposed = 1.63, 95% confidence interval (CI): 1.22, 2.17; Ptrend

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Gale Document Number: GALE|A324771572