A rare side effect of levosulpiride: Galactorrhea.

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Date: Jan-Feb 2021
From: Indian Journal of Pharmacology(Vol. 53, Issue 1)
Publisher: Medknow Publications and Media Pvt. Ltd.
Document Type: Letter to the editor
Length: 534 words
Lexile Measure: 1420L

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Byline: Subodh. Mahto, Nagina. Agarwal, Kritika. Gupta, Biswa. Patra

Sir,

Levosulpiride mainly acts by blocking D2 dopaminergic receptors located on the presynaptic membrane of the gastrointestinal tract and central nervous system dopaminergic pathways. The central D2 receptor antagonism is responsible for the therapeutic as well as the adverse effect of hyperprolactinemia.[1] Rabeprazole and levosulpiride combination pill is now being universally used for dyspeptic symptoms. However, long-term users are developing a major complication. Herein, we report a case of a patient who received levosulpiride for a duration of 5 months and developed galactorrhea.

A 26-year-old married female presented with a history of galactorrhea for last 3 months. She had no history of headache or visual disturbances. The patient had complains of dyspepsia for the last 6 months and was receiving rabeprazole (20 mg) plus...

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Gale Document Number: GALE|A662111359