Trends of fluid requirement in dengue fever and dengue haemorrhagic fever: a single centre experience in Sri Lanka

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From: BMC Research Notes(Vol. 8, Issue 1)
Publisher: BioMed Central Ltd.
Document Type: Article
Length: 3,272 words
Lexile Measure: 1440L

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Abstract :

Background Meticulous fluid management is the mainstay of treatment in dengue fever that is currently governed by consensus guidelines rather than by strong research evidence. To examine this issue we audited the fluid requirement of a cohort of adult patients with dengue fever (DF) and dengue haemorrhagic fever (DHF) in a tertiary care clinical setting. Results This retrospective cohort study was conducted from July 2012 to January 2013 in Teaching Hospital, Peradeniya, Sri Lanka. Adult patients with confirmed dengue infection managed according to the national and WHO guidelines were included. Their fluid requirement was audited once data collection was over in both DF and DHF groups. Out of 302 patients, 209 (69%) had serological confirmation of dengue infection, comprising 62 (30%) patients gone into critical phase of DHF. Mean age of the DHF group was 30 years (range 12-63 years) and included more males (n = 42, 68%, p Conclusions Patients in critical phase of DHF required a higher volume of fluids from the 3.sup.rd day of fever and again on 5.sup.th to 7.sup.th day of fever. Despite being an audit, these finding could be useful in future updates of guidelines and designing research. Keywords: Dengue fever, Dengue haemorrhagic fever, Critical phase, Fluid management

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Gale Document Number: GALE|A541620290