Sentinel-node biopsy or nodal observation in melanoma

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From: The New England Journal of Medicine(Vol. 355, Issue 13)
Publisher: Massachusetts Medical Society
Document Type: Article
Length: 71 words

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Abstract :

The Multimember Selective Lymphadenectomy Trial (MSLT) was initiated to study the usefulness of sentinel-node biopsy in the identification of patients with clinically occult nodal metastases and to evaluate the clinical effect of immediate, complete lymphadenectomy in patients with tumor-positive sentinel nodes. Findings indicate that sentinel-node biopsy has staging and prognostic value in patients with intermediate-thickness melanoma and coupled with immediate complete lymphadenectomy, improve survival among patients with a tumor-positive sentinel node.

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Gale Document Number: GALE|A153385723