Total synthesis of asimicin and bullatacin

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From: Journal of Organic Chemistry(Vol. 65, Issue 19)
Publisher: American Chemical Society
Document Type: Article
Length: 49 words

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Abstract :

Synthesis of Annonaceous acetogenins, comprising asimicin and bullatacin, by naked carbon skeleton strategy, the convergent , and a hybrid approach is described. A library of 64 sterioisomers of the two compounds is constructed using all the above three approaches. Asimicin and bullatacin possess antitumor, antimalarial, immunosuppressive, and pesticidal properties.

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Gale Document Number: GALE|A65950266