Uncommon cause of acute liver failure with encephalopathy

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Date: Aug. 2018
Publisher: Medknow Publications and Media Pvt. Ltd.
Document Type: Letter to the editor
Length: 664 words
Lexile Measure: 1220L

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Byline: Subodh. Mahto, Ankita. Sheoran, Atul. Goel, Nagina. Agarwal


Jaundice with encephalopathy is a common presentation of many tropical infections. The hepatic involvement in tropical infections can range from mild, transient elevation in enzymes to acute liver failure (ALF).[1] Herein, we present a case of ALF with encephalopathy caused by scrub typhus.

A 22-year-old male, the resident of New Delhi, presented with complaints of high-grade fever for 5 days. He also had right upper quadrant abdominal pain and jaundice, which developed 2 days after the onset of fever. The patient developed altered sensorium 1-day before the presentation. On examination, the patient was unconscious with a Glasgow coma scale of E3V3M4. His temperature was 104[degrees]F. His pulse rate was 105/min and blood pressure was 120/80 mmHg. Icterus was present. Central nervous system examination revealed no neck rigidity. Bilateral pupils were normal and reactive to light and bilateral planters were flexor. Rest of general and systemic examination revealed no obvious abnormality.

Laboratory tests revealed 14.3 gm% hemoglobin...

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Gale Document Number: GALE|A551305909