Characteristics of sickle cell patients with frequent emergency department visits and hospitalizations

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From: PLoS ONE(Vol. 16, Issue 2)
Publisher: Public Library of Science
Document Type: Report
Length: 5,262 words
Lexile Measure: 1490L

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Abstract :

Vaso-occlusive episodes (VOEs) are a hallmark of sickle cell disease (SCD), and account for 90% of health care encounters for this patient population. The Cooperative Study of Sickle Cell Disease, a large study enrolling 3000 patients, showed that the majority of SCD patients (80%) experienced 0-3 major pain crises/year. Only a small minority (~5%) experienced [greater than or equal to]6 VOEs/year. Our study sought to further understand this difference in VOE frequency between SCD patients. We analyzed 25 patients (13M/12F, mean age of 28.8) with [greater than or equal to]6 ED visits or hospitalizations/year (high utilizers), and compared these with 9 patients (6M/3F, mean age of 37.6) who had [less than or equal to]2 ED visits or hospitalizations/year (low utilizers). All subjects were given a demographic survey along with questionnaires for depression, anxiety, and Health Locus of Control. Each subject then underwent quantitative sensory testing (QST) with three different modalities: pressure pain sensitivity, heat and cold sensitivity, and Von Frey monofilament testing. Laboratory and clinical data were collected through subjects' medical records. CBC and chemistry analysis showed high utilizers had higher WBC (p

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Gale Document Number: GALE|A652669330