Seroprevalence of Brucellosis: A 10-year experience at a tertiary care center in north India

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Date: April-June 2012
Publisher: Medknow Publications and Media Pvt. Ltd.
Document Type: Letter to the editor; Report
Length: 919 words
Lexile Measure: 1460L

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Byline: Suma. Appannanavar, Kusum. Sharma, Subhash. Verma, Meera. Sharma


Brucellosis is an important but neglected zoonotic disease having a worldwide distribution. The disease contributes significantly to economic losses for animal handlers. Transmission to humans occurs through contact with animals, animal tissue contaminated with the organisms or through ingestion of contaminated products. Worldwide, around five lakh human cases occur every year. [sup][1] The disease is more prevalent in the Mediterranean region, western Asia, parts of Africa and Latin America. A higher incidence of the disease can be expected in India, which has a major agrarian population who come in close contact with domestic animals. It has been estimated that the true incidence may be 25-times higher than the reported incidence due to misdiagnosis and underreporting, largely due to lack of proper laboratory facilities in remote areas as well as poor exchange of information between veterinary and public health services. Very few reports are available on the prevalence of human brucellosis in our region. [sup][2],[3] Here, we report a high seroprevalence of brucellosis (9.94%) in patients presenting with pyrexia of unknown origin (PUO) from a tertiary care center in North India.

A total of 1448 serum samples from cases of pyrexia of unknown origin submitted to our center over a period of 10 years from January 2000 to June 2011 were screened for evidence of brucellosis. All the samples were...

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Gale Document Number: GALE|A295466051