The impact of comorbid depression on recovery from personality disorders and improvements in psychosocial functioning: Results from a randomized controlled trial

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Publisher: Elsevier Science Publishers
Document Type: Clinical report
Length: 337 words

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To link to full-text access for this article, visit this link: Byline: Fritz Renner, Lotte L.M. Bamelis, Marcus J.H. Huibers, Anne Speckens, Arnoud Arntz Abstract: Depressive disorders often co-occur with personality disorders. The extent to which depressive disorders influence treatment outcome in personality disorders remains unclear. The aim of this study was to determine the impact of co-morbid depression on recovery from personality disorders and improvements in psychosocial functioning. This study drew data from a randomized-controlled trial in which patients (N = 320) with cluster-c (92%), paranoid, histrionic and/or narcissistic personality disorders received schema-therapy, treatment-as-usual, or clarification-oriented psychotherapy. Recovery from personality disorders at three-year follow-up and improvements in psychosocial functioning over a course of three years was predicted by the diagnostic status of depressive disorders at baseline using mixed model regression analyses. Based on the number of axis-I and axis-II disorders, personality disorder severity and global symptomatic distress and functioning a baseline severity index was computed and included in subsequent analyses to test the specificity of baseline depression in predicting outcomes. Patients with co-occurring depression reported higher baseline severity compared to patients without co-occurring depression. Depression at baseline was associated with lower recovery rates at three-year follow-up (p = 0.01) but this effect disappeared after controlling for baseline severity. Patients with depression at baseline reported higher psychosocial impairments throughout treatment (p Author Affiliation: (a) Department of Clinical Psychological Science, Maastricht University, The Netherlands (b) Department of Clinical Psychology, VU University Amsterdam, The Netherlands (c) Department of Psychiatry, Radboud University Nijmegen, The Netherlands (d) Department of Clinical Psychology, University of Amsterdam, The Netherlands Article History: Received 4 April 2014; Revised 3 September 2014; Accepted 15 September 2014

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Gale Document Number: GALE|A394916040