Background Gestational iron deficiency (ID) can be deleterious to mother and fetus. However, iron status is not routinely measured during pregnancy in Ghana. Therefore, the scope of ID in this population is unknown. Objective To determine the prevalence of anemia and ID across pregnancy in the Central Region of Ghana. Methods Women were recruited during their 1.sup.st trimester of pregnancy ( Results Participants were 27.1 ± 5.2 years, on average. Prevalence of anemia (Hb Conclusions ID is prevalent in pregnant Ghanaian women, especially during the 3.sup.rd trimester. Anemia is a major public health problem during pregnancy in Ghana with a significant proportion due to factors other than ID.