Effects of soluble fiber (Plantago ovata husk) on plasma lipids, lipoproteins, and apolipoproteins in men with ischemic heart disease

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From: American Journal of Clinical Nutrition(Vol. 85, Issue 4)
Publisher: American Society for Clinical Nutrition, Inc.
Document Type: Author abstract; Clinical report
Length: 287 words

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Abstract :

Background: New dietary strategies to reduce cardiovascular disease (CVD) risk include the addition of fiber to the diet. The effect of soluble-fiber consumption derived from Plantago ovata husk on lipid risk factors in patients with CVD is unknown. Objective: We compared the effects of soluble fiber (P. ovata husk) with those of insoluble fiber (P. ovata seeds) on plasma lipid, lipoprotein, and apolipoprotein (apo) concentrations within a CVD secondary prevention program. Design: In a randomized, crossover, controlled, single-blind design, 28 men with CVD (myocardial infarction or stable angina) and an LDL-cholesterol concentration [less than or equal to] 3.35 mmol/L consumed for 8 wk, under controlled conditions, a low-saturated-fat diet supplemented with 10.5 g P. ovata husk/d or 10.5 g P. ovata seeds/d. Fasting plasma lipid concentrations and polymorphisms of genes involved in lipid metabolism, such as apo A-IV, apo E, and fatty acid-binding protein, were measured. Results: Plasma triacylglycerol decreased (6.7%; P Conclusion: In the secondary prevention of CVD, P. ovata husk intake induces a more beneficial effect on the cardiovascular lipid risk-factor profile than does an equivalent intake of insoluble fiber. KEY WORDS Dietary fiber, Plantago ovam (Ispaghula husk), psyllium, secondary prevention of cardiovascular disease, blood lipids, low saturated fat, FABP2 gene, apo A-IV gene, apo E gene, polymorphism

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Gale Document Number: GALE|A162832943