Intensive care unit admission for pandemic (H1N1) 2009, Reunion Island, 2009

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From: Emerging Infectious Diseases(Vol. 17, Issue 1)
Publisher: U.S. National Center for Infectious Diseases
Document Type: Report
Length: 1,153 words
Lexile Measure: 1270L

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To the Editor: We report results of the prospective surveillance system established in the largest intensive care unit (ICU) of Reunion Island (25 beds). This system covers 500,000 residents (62% of the total population) and monitors the daily status of patients >17 years of age who had a positive reverse transcription-PCR (RT-PCR) for pandemic (H1N1) 2009 virus. Reunion Island is a French overseas territory in the Southern Hemisphere, with health care facilities similar to those of mainland France. Patients were followed up until discharge from the ICU or death. Data were collected during July 15-September 30, 2009.

Of 148 patients with confirmed pandemic (H1N1) 2009 infection admitted to the hospital, 13 (9%) patients (8 female) were admitted to the ICU. These corresponded to 7% of all 187 patients admitted to the ICU during the same period. Median age was 39.4 ([+ or -]19) years (range 17-69 years). Ten patients were admitted for respiratory failure related to viral pneumonitis, 1 for pulmonary edema with severe chronic coronary insufficiency, 1 for congenital adrenal insufficiency with reversible multiple organ failure, and 1 for status epilepticus. Eleven (85%) patients had underlying concurrent medical conditions: 3 were overweight (body mass indexes 38, 32, and 29.3 kg/[m.sup.2]); 1 was pregnant and had asthma.

Four (31%) patients died. One was a 28-year-old woman with cerebral motor infirmity and severe chronic restrictive respiratory failure. An 18-year-old woman with aplasia after receipt of an allograft for Hodgkin lymphoma died of cerebral hemorrhage while receiving extracorporeal membrane oxygenation. A 52-year-old man admitted for pulmonary edema with severe coronary insufficiency died of multiple organ failure. A 33-year-old man with no known concurrent medical conditions died of acute respiratory distress syndrome. Time from ICU admission to death ranged from 15...

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Gale Document Number: GALE|A248578481