Efficacy of phototherapy devices and outcomes among extremely low birth weight infants: multi-center observational study

Citation metadata

From: Journal of Perinatology(Vol. 33, Issue 2)
Publisher: Nature Publishing Group
Document Type: Report
Length: 5,214 words
Lexile Measure: 1580L

Document controls

Main content

Abstract :

Objective: Evaluate the efficacy of phototherapy (PT) devices and the outcomes of extremely premature infants treated with those devices. Study Design: This substudy of the National Institute of Child Health and Human Development Neonatal Research Network PT trial included 1404 infants treated with a single type of PT device during the first 24 [+ or -] 12 h of treatment. The absolute (primary outcome) and relative decrease in total serum bilirubin (TSB) and other measures were evaluated. For infants treated with one PT type during the 2-week intervention period (n - 1223), adjusted outcomes at discharge and 18 to 22 months corrected age were determined. Result: In the first 24 h, the adjusted absolute (mean ([+ or -] s.d.)) and relative (%) decrease in TSB (mg [dl.sup.-1]) were: light-emitting diodes (LEDs) -2.2 ([+ or -]3), -22%; Spotlights -1.7 ([+ or -]2), -19%; Banks -1.3 ([+ or -] 3) -8%; Blankets -0.8 ([+ or -] 3) -1%; (P Conclusion: LEDs achieved the greatest initial absolute reduction in TSB but were similar to Spots in the other performance measures. Long-term effects of PT devices in extremely premature infants deserve rigorous evaluation. Journal of Perinatology (2013) 33, 126-133; doi: 10.1038/jp.2012.39; published online 12 April 2012 Keywords: extremely low birth weight; neonatal jaundice; neurodevelopmental outcome; phototherapy

Source Citation

Source Citation   

Gale Document Number: GALE|A318493340