Vaccine update: The latest recommendations from ACIP: Here are the latest recommendations on the hepatitis, pneumococcal, zoster, rabies, and dengue vaccines.

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Date: Mar. 2022
From: Journal of Family Practice(Vol. 71, Issue 2)
Publisher: Jobson Medical Information LLC
Document Type: Article
Length: 1,789 words
Lexile Measure: 1480L

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In a typical year, the Advisory Committee on Immunization Practices (ACIP) has three 1.5- to 2-day meetings to make recommendations for the use of new and existing vaccines in the US population. However, 2021 was not a typical year. Last year, ACIP held 17 meetings for a total of 127 hours. Most of these were related to vaccines to prevent COVID-19. There are now 3 COVID-19 vaccines authorized for use in the United States: the 2-dose mRNA-based Pfizer-BioNTech/ Comirnaty and Moderna COVID-19 vaccines and the single-dose adenovirus, vector-based Janssen (Johnson & JoJtnson) COVID-19 vaccine.

TABLE 1 (1) includes the actions taken by the ACIP from late 2020 through 2021 related to COVID-19 vaccines. All of these recommendations except 1 occurred after the US Food and Drug Administration (FDA) approved the product using an emergency use authorization (EUA). The exception is the recommendation for use of the Pfizer-BioNTech COVID-19 vaccine (BNT162b2) for those ages 16 years and older, which was approved under the normal process 8 months after widespread use under an EUA.

Hepatitis B vaccine now for all nonimmune adults up through 59 years

Since the introduction of hepatitis B (HepB) vaccines in 1980, the incidence of hepatitis B virus (HBV) infections in the United States has been reduced dramatically; there were an estimated 287,000 cases in 19852 and 19,200 in 2014. (3) However, the incidence among adults has not declined in recent years and among some age groups has actually increased. Among those ages 40 to 49 years, the rate went from 1.9 per 100,000 in 2011 (4) to 2.7 per 100,000 population in 2019. (5) In those ages 50 to 59, there was an increase from 1.1 to 1.6 per 100,000 population over the same period of time. (4,5)

Recommendations for using HepB vaccine in adults have been based on risk that involves individual behavior, occupation, and medical conditions (table 2 (6)). The presence of these risk factors is often unknown to medical professionals, who rarely ask about or document them. And patients can be reluctant to disclose them for fear of being stigmatized. The consequence has been a low rate of vaccination in at-risk adults.

At its November 2021 meeting, ACIP accepted the advice of the Hepatitis Work Group to move to a universal adult recommendation through age 59. (7) ACIP believed that the incidence of acute infection in those ages 60 and older was too low to merit a universal recommendation. The new recommendation states that all adults through age 59 years who are not immune to HBV through vaccination or prior infection should receive a HepB vaccine series, as should those 60 years and older with a risk factor (table 2 (6))....

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Gale Document Number: GALE|A703998654