Effects of captopril and angiotensin II receptor blockers (AT.sub.1, AT.sub.2) on myocardial ischemia-reperfusion induced infarct size

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Date: Dec. 2011
From: Cytokine(Vol. 56, Issue 3)
Publisher: Elsevier B.V.
Document Type: Report
Length: 126 words

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Abstract :

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.cyto.2011.09.002 Byline: Hakan Parlakpinar (a), Mehmet Kaya Ozer (b), Ahmet Acet (a) Keywords: Captopril; Losartan; PD123319; AT.sub.2 receptor; Myocardial ischemia-reperfusion Abstract: a* Captopril and losartan showed beneficial effects against MI/R-induced cardiac injury. a* Our cardioprotective findings were confirmed by TTC staining method and hemodynamic parameters. a* The cardioprotective mechanism was discussed in the view of angiotensin receptors (AT.sub.1 and AT.sub.2). a* AT.sub.2 receptor agonists could be a function for prevention from MI/R injury. Author Affiliation: (a) Division of Pharmacology, Department of Medicine, University of Inonu, 44280 Malatya, Turkey (b) Division of Pharmacology, Department of Medicine, University of Suleyman Demirel, Isparta, Turkey Article History: Received 6 July 2011; Revised 5 August 2011; Accepted 2 September 2011

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Gale Document Number: GALE|A272899850