Efficacy of budesonide/formoterol and tiotropium combination for the treatment of Chinese patients with chronic obstructive pulmonary disease

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From: Medicine(Vol. 97, Issue 22)
Publisher: Lippincott Williams & Wilkins, WK Health
Document Type: Author abstract; Report
Length: 248 words

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Abstract :

Byline: Jun-fei Feng, Department of Respiratory Medicine; Guo-rong Ding, Emergency Department, Hangzhou Fuyang Hospital of Traditional Chinese Medicine; Yan-zhong Xie, Emergency Department, Hangzhou Fuyang Hospital of Traditional Chinese Medicine; Dejun Zhao, Department of Respiratory Medicine, The People's Hospital of Fuyang, Hangzhou; Xuehui Wang, Department of Respiratory Medicine, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China. Abstract This study investigated the efficacy and safety of budesonide/formoterol (B/F) and tiotropium combination in the management of chronic obstructive pulmonary disease (COPD) in Chinese patients.Between January 2015 and November 2017, 113 eligible Chinese patients with COPD were included and divided into an intervention group and a control group. Sixty-three patients in the intervention group underwent B/F combined tiotropium, while 50 patients in the control group received tiotropium alone. The primary outcome was severity of dyspnea on exertion (DOE), measured by the 6-minute walk test (6MWT) scale. The secondary outcomes included lung function, measured by the forced expiratory volume in 1 second (FEV1), quality of life, measured by the St. George's Respiratory Questionnaire (SGRQ), and adverse events. All outcomes were measured at the end of 12-week treatment.B/F and tiotropium combination showed greater efficacy in DOE (P

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Gale Document Number: GALE|A543063275