Cross-sectional microhardness of bovine enamel subjected to three paediatric liquid oral medicines: an in vitro study

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Publisher: European Academy of Paediatric Dentistry
Document Type: Report
Length: 3,618 words
Lexile Measure: 1400L

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Abstract :

AIM: This study aimed to investigate the in vitro effects of three paediatric liquid oral medicines on bovine dental enamel subsurfaces under pH cycling conditions.G METHODS: Bovine enamel blocks were evaluated for surface hardness at baseline for sample selection. 52 intact bovine enamel blocks (16[mm.sup.2]) were randomly divided into four groups (n = 13) according to the immersion treatments: G1: antibiotic (Klaricid[R]), G2: antihistamine (Claritin[R]), G3: antihistamine (Dimetapp[R]) and G4: control (de-ionised water). The blocks were submitted to pH cycling treatments twice a day for 12 days. The medicines were evaluated for pH, viscosity, and concentration of calcium, phosphate and fluoride. After the treatment period, cross-sectional microhardness (CSMH) measurements of the enamel blocks were taken and the data, expressed in Knoop hardness number (kg/[mm.sup.2]) was used to calculate the AS. STATISTICS: ANOVA followed by the Tukey test were used for statistical analyses (p G1 G2 G3 and G1 G2 G3 G4 respectively. Regarding the demineralisation pattern, the following results were observed: G4 G3 G2 G1. Compared to the control, the antibiotic and both the antihistamines provoked less demineralisation of the enamel blocks (p Key words: Paediatric medicines, enamel, microhardness

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Gale Document Number: GALE|A308598724