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• Characterizing allele- and haplotype-specific copy numbers in single cells with CHISEL.

  Authors:Simone Zaccaria and Benjamin J. RaphaelFrom:Nature Biotechnology (Vol. 39, Issue 2) Peer-Reviewed

  Feb. 202112,604 words Report 1650LSingle-cell barcoding technologies enable genome sequencing of thousands of individual cells in parallel, but with extremely low sequencing coverage (<0.05×) per cell. While the total copy number of large multi-megabase...