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From:Journal of Clinical Investigation (Vol. 131, Issue 23) Peer-Reviewed
Preexisting memory CD[4.sup.+] T cells contribute to the primary response in an HIV-1 vaccine trial.
Naive and memory CD[4.sup.+] T cells reactive with human immunodeficiency virus type 1 (HIV-1) are detectable in unexposed, unimmunized individuals. The contribution of preexisting CD[4.sup.+] T cells to a primary immune...