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    Academic Journals

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• Estimation of metabolic syndrome in acanthosis nigricans - A hospital based cross-sectional study.

  Authors:Nicely Philip, Banavasi Girisha, Shricharith Shetty, Ashna Pinto, and Tonita NoronhaFrom:Indian Journal of Dermatology (Vol. 67, Issue 1) Peer-Reviewed

  Jan-Feb 20222,857 words Report 1400LByline: Nicely. Philip, Banavasi. Girisha, Shricharith. Shetty, Ashna. Pinto, Tonita. Noronha Background and Objectives: Acanthosis nigricans is characterized by hyperpigmentation and velvet-like thickening of the...

• A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease.

  Authors:James A Timmons, Andrew Anighoro, Robert J Brogan, Jack Stahl, Claes Wahlestedt, David Gordon Farquhar, et al.From:eLife (Vol. 11) Peer-Reviewed

  Jan. 17, 202221,282 words Article 1550LInsulin resistance (IR) contributes to the pathophysiology of diabetes, dementia, viral infection, and cardiovascular disease. Drug repurposing (DR) may identify treatments for IR; however, barriers include uncertainty...

• Sirt1 Mediates Vitamin D Deficiency-Driven Gluconeogenesis in the Liver via mTorc2/Akt Signaling.

  Authors:Qi Yuan, Ridong Zhang, Mengyue Sun, Xiao Guo, Jinglei Yang, Wen Bian, et al.From:Journal of Diabetes Research (Vol. 2022) Peer-Reviewed

  Jan. 29, 20228,543 words Article 1380LAs an active form of vitamin D (VD), 1,25-dihydroxyvitamin D (1,25(OH)[sub.2]D[sub.3]) is involved in the development of many metabolic diseases, such as diabetes, autoimmune diseases, and tumours. While prospective...

• Adiponectin levels and its relation with insulin secretion and insulin sensitivity in a group of sub-Saharan African women with polycystic ovary syndrome.

  Authors:Audrey Synthia Momo, Vicky Jocélyne Ama Moor, Aurel T. Tankeu, Falmata Amazia, Guy Sadeu Wafeu, Magellan Guewo-Fokeng, et al.From:BMC Research Notes (Vol. 15, Issue 1) Peer-Reviewed

  Jan. 28, 20222,766 words Article 1310LObjectives Low levels of adiponectin have been reported in Polycystic Ovary Syndrome (PCOS). In sub-Saharan Africa, little data are available on the topic. We aimed to investigate the levels of adiponectin and its...

• Outsourcing's Race Toward Novelty: Recent developments in the outsourcing industry include a focus on early development services, biosimilar production, and RNA technology.

  Author:Grant PlayterFrom:Pharmaceutical Technology Europe (Vol. 34, Issue 1) Peer-Reviewed

  Jan. 2022787 words Article 1440LBio/pharma is a fast-paced industry that is continuously innovating via new technologies and techniques. The determination of what, if anything, should be outsourced throughout the development, manufacturing, and...

• Metabolic (Dysfunction)-Associated Fatty Liver Disease in Chinese Patients with Type 2 Diabetes from a Subcenter of the National Metabolic Management Center.

  Authors:Conghui Guan, Songbo Fu, Donghu Zhen, Kuan Yang, Jinyang An, Yapei Wang, et al.From:Journal of Diabetes Research (Vol. 2022) Peer-Reviewed

  Jan. 28, 20226,331 words Article 1520LBackground. Few studies have investigated the epidemiological metabolic (dysfunction) associated with fatty liver disease (MAFLD) in China, especially among those with type 2 diabetes. Methods. We recruited 3553 patients...

• Creatinine-to-body weight ratio is a predictor of incident diabetes: a population-based retrospective cohort study.

  Author:Jiacheng HeFrom:Diabetology & Metabolic Syndrome (Vol. 14, Issue 1) Peer-Reviewed

  Jan. 15, 20224,539 words Report 1450LPurpose Creatinine to body weight (Cre/BW) ratio is considered the independent risk factor for incident type 2 diabetes mellitus (T2DM), but research on this relationship is limited. The relationship between the Cre/BW...

• The Potential Therapeutic Effect of Orexin-Treated versus Orexin-Untreated Adipose Tissue-Derived Mesenchymal Stem Cell Therapy on Insulin Resistance in Type 2 Diabetic Rats.

  Authors:Amy F. Boushra, Rania H. Mahmoud, Shymaa E. Ayoub, Rehab A. Mohammed, Hanan A. Shamardl, and Amani M. El Amin AliFrom:Journal of Diabetes Research (Vol. 2022) Peer-Reviewed

  Jan. 17, 20226,763 words Article 1370LType 2 diabetes mellitus is a chronic metabolic disease characterized by resistance to peripheral insulin actions. Mesenchymal stem cells have been studied for years in T2DM therapy, including adipose tissue-derived...

• Phenotype of higher post-load insulin response as a predictor of all-cause mortality and cardiovascular mortality in the Chinese non-diabetic population.

  Authors:Xiaoxia Shen, Siyao He, Jinping Wang, Xin Qian, Hui Wang, Bo Zhang, et al.From:Diabetology & Metabolic Syndrome (Vol. 14, Issue 1) Peer-Reviewed

  Jan. 28, 20223,275 words Article 1560LAim This study aimed to assess whether a higher insulin response increased the long-term risk of mortality in a non-diabetic population. Methods A total of 446 people with normal glucose tolerance (NGT) or impaired...

• Obesity, Adipose Tissue, and Inflammation Answered in Questions.

  Authors:Vanessa A. Guerreiro, Davide Carvalho, and Paula FreitasFrom:Journal of Obesity (Vol. 2022) Peer-Reviewed

  Jan. 22, 202211,494 words Article 1610LBackground. Obesity is a global health problem of epidemic proportions, which is characterized by increased adipose tissue (AT) mass and significant repercussions in different body apparati and systems. AT is a special...

• Salivary IGF-1 and Alkaline Phosphatase-Based Modeling for Skeletal Maturity Prediction in Orthodontic Patients.

  Authors:Asma Sookhakian, Maryam Zahed, Hamidreza Pakshir, and Shabnam AjamiFrom:BioMed Research International (Vol. 2022) Peer-Reviewed

  Jan. 21, 20225,321 words Report 1330LBackground/Objectives. The correct identification of the different stages of skeletal maturity is a crucial issue in orthodontic diagnosis and treatment planning decisions. The hand-wrist analysis and cervical vertebral...

• Resveratrol Alleviates Skeletal Muscle Insulin Resistance by Downregulating Long Noncoding RNA.

  Authors:Zhihong Liu, Zhimei Zhang, Guangyao Song, Xing Wang, Hanying Xing, and Chao WangFrom:International Journal of Endocrinology (Vol. 2022) Peer-Reviewed

  Jan. 19, 20227,832 words Article 1180LLong noncoding RNA (lncRNA) is a crucial factor in the progression of insulin resistance (IR). Resveratrol (RSV) exhibits promising therapeutic potential for IR. However, there are few studies on whether RSV improves IR...

• A PDK-1 allosteric agonist neutralizes insulin signaling derangements and beta-amyloid toxicity in neuronal cells and in vitro.

  Authors:Henry Querfurth, John Marshall, Keykavous Parang, Mengia S. Rioult-Pedotti, Rakesh Tiwari, Bumsup Kwon, et al.From:PLoS ONE (Vol. 17, Issue 1) Peer-Reviewed

  Jan. 21, 202215,916 words Report 1340LThe Alzheimer's brain is affected by multiple pathophysiological processes, which include a unique, organ-specific form of insulin resistance that begins early in its course. An additional complexity arises from the...

• Sleep-Disordered Breathing Tied to Insulin Resistance in Pregnancy.

  From:Clinical Advisor

  Jan. 11, 2022224 words Brief article 1350LHealthDay News — Maternal sleep-disordered breathing (SDB) is associated with insulin resistance in early pregnancy, according to a study published online Jan. 6 in SLEEP. Laura Sanapo, MD, from the Miriam Hospital in...

• The association of Schistosoma and geohelminth infections with [beta]-cell function and insulin resistance among HIV-infected and HIV-uninfected adults: A cross-sectional study in Tanzania.

  Authors:George PrayGod, Suzanne Filteau, Nyagosya Range, Kaushik Ramaiya, Kidola Jeremiah, Andrea M. Rehman, et al.From:PLoS ONE (Vol. 17, Issue 1) Peer-Reviewed

  Jan. 25, 20226,255 words Report 1600LObjectives Data on the role of helminths on diabetes in Africa are limited. We investigated whether Schistosoma and geohelminth infections are associated with [beta]-cell function and insulin resistance among adults....

• The improvement of insulin level after hydrogen-rich water therapy in streptozotocin-induced diabetic rats.

  Authors:Ekowati Retnaningtyas, Budi Susatia, Siti Nur Arifah, and Sri Rahayu LestariFrom:Veterinary World (Vol. 15, Issue 1)

  Jan. 20223,816 words Article 1310LBackground and Aim: Water plays a pivotal role in the body. Alteration of the fluid balance promotes metabolic disorder, thus leading to the development of various diseases, such as diabetes mellitus (DM). Hydrogen-rich...

• Repeated glucose spikes and insulin resistance synergistically deteriorate endothelial function and bardoxolone methyl ameliorates endothelial dysfunction.

  Authors:Kazuma Ogiso, Sigfrid Casmir Shayo, Shigeru Kawade, Hiroshi Hashiguchi, Takahisa Deguchi, and Yoshihiko NishioFrom:PLoS ONE (Vol. 17, Issue 1) Peer-Reviewed

  Jan. 24, 202212,094 words Report 1420LBackground Both insulin resistance and postprandial glucose spikes are known for their potential to induce vascular endothelial dysfunction in individuals with metabolic syndrome. However, these factors are...

• Comparison of insulin sensitivity between healthy neonatal foals and horses using minimal model analysis.

  Authors:Hannah M. Kinsella, Laura D. Hostnik, Hailey A. Snyder, Sarah E. Mazur, Ahmed M. Kamr, Teresa A. Burns, et al.From:PLoS ONE (Vol. 17, Issue 1) Peer-Reviewed

  Jan. 14, 20225,934 words Report 1540LThe equine neonate is considered to have impaired glucose tolerance due to delayed maturation of the pancreatic endocrine system. Few studies have investigated insulin sensitivity in newborn foals using dynamic testing...

• Differences in gut microbiome by insulin sensitivity status in Black and White women of the National Growth and Health Study (NGHS): A pilot study.

  Authors:Candice A. Price, Guillaume Jospin, Kristy Brownell, Jonathan A. Eisen, Barbara Laraia, and Elissa S. EpelFrom:PLoS ONE (Vol. 17, Issue 1) Peer-Reviewed

  Jan. 19, 20228,446 words Report 1440LThe prevalence of overweight and obesity is greatest amongst Black women in the U.S., contributing to disproportionately higher type 2 diabetes prevalence compared to White women. Insulin resistance, independent of body...

• Frequency of obesity and metabolic syndrome in childhood leukemia and lymphoma survivors.

  Authors:Ä°brahim Kartal, Abdurrahman Alaçam, Ayhan DaÄdemir, Cengiz Kara, OÄuz Salih Dinçer, Canan Albayrak, et al.From:Diabetology & Metabolic Syndrome (Vol. 14, Issue 1) Peer-Reviewed

  Jan. 24, 20224,851 words Article 1560LObjectives In this study, it was aimed to determine the prevalence and clinical features of obesity and metabolic syndrome, which are long-term effects of survivors after treatment in children with leukemia and...